Celebration time in Nijmegen
Our clinical site in Nijmegen knows how to celebrate! For the Clouse-Out visit they even had some NILVAD style cake.
New clinical monitor for Nijmegen
Hi! I am Samantha Fleuren and in January of 2016 I succeeded my colleague Fenna Mahler as monitor of the NILVAD project for the Nijmegen site. After I finished my study Molecular Life Sciences at the Radboud University, I started working as a quality officer in the Radboud university medical center in Nijmegen, the Netherlands. Apart from the NILVAD project I am involved in various other clinical trials as a monitor. I find it very exciting to be part of such a large international trial as NILVAD and I am happy to be able to support the team towards the end of the trial.
New clinical monitor for the greek clinical sites
Mrs Lamprini Pikoula is a Biologist graduated from University of Patras/ Biology Department on July 2010. On 2014 she completed her postgraduate studies in University of Athens and got her master’s degree in Microbial Biotechnology. She worked almost two years as an undergraduate student at University General Hospital of Patras on a retrospective analysis of Candidemia in hospitalized patients, while a few years later she worked as an intern in Siemens Healthcare sector.
Lamprini is a CORONIS employee and she is involved in NILVAD project as Greek Monitor since 24th August 2015. Cooperation with Mrs Cregg, Mrs Adams and the rest of study team members is really creative and exciting. Lamprini is the responsible CRA for three participating sites in Thessaloniki.
Besides of Alzheimer’s Disease, Lamprini is also implicated in different therapeutic areas including immunology, gastroenterology and oncology in frame of other interventional clinical trials currently running within CORONIS Company.
New research assistant at the NILVAD project office
Dr Hannah McCarthy started as a Research Assistant at the NILVAD Project Office in Dublin on February 1st 2016. Hannah works closely with Fiona Cregg in assisting with the project management and daily operations of the NILVAD project. Hannah has a PhD in Microbiology from the National University of Ireland Galway and previous to this role she worked as the Clinical Trial Coordinator of a Pfizer funded observational trial at the Royal College of Surgeons in Ireland which was run out of Beaumont Hospital in Dublin. Hannah is enjoying working with the NILVAD teams and being able to assist them in maintaining the smooth running of the trial. “The fact that there are so many sites and countries involved in the project means no two days in the office are the same. NILVAD certainly keeps you on your toes!”
Substudy protocols have been submitted to the British Medical Journal
In February 2016 a paper was submitted by the Nilvad team to the British Medical Journal. The paper describes the protocols for the four sub studies being conducted during the Nilvad study. These are:
- The blood and genetic biomarker sub study.
- The cerebrospinal fluid biomarker sub study.
- The frailty sub study.
- The cerebral blood flow sub study.
A link to the paper will be shared on the website once the submission has been approved.
New hungarian clinical monitor
Dr Péter Balázs is working for a Clinical Research Organization (CPS Cortex Ltd.) in Hungary as a Clinical Research Associate since 2014 and in 2015 took on the role of Hungarian monitor on the NILVAD project. Péter graduated from the University of Debrecen as a pharmacist and after graduation, he worked in the pharmaceutical industry. The two years he spent working in a non-stop pharmaceutical environment was not an enjoyable experience for him and after some research he decided he would like to work as a CRA. Péter enjoys the challenging nature of the job and communicating and working with a lot of intelligent people. This inspires him. "When you are faced with different problems on site or at the office you have to be able to solve them, and I think I’m good at it." In particular Péter enjoys the feasibility and contract management aspects of a study.
NILVAD recruitment finished
Recruitment finished in April 2015 and a total of 511 people were recruited to the study. The follow-up period for every participant is 18 months and follow-up will continue until early November 2016. After this time analysis of the data will be conducted and is expected to continue until early 2017.
30 May 2014
Brain Health Awareness Day at St James`s Hospital Dublin
On May 27th 2014, a Brain Health Awareness Day was organised at St James’s Hospital in Dublin.
The Awareness Day was aimed at members of the general public who were visiting the hospital. A stand was set up in the foyer, which contained information and leaflets about how to maintain a healthy brain. The ‘Hello Brain’ campaign was also promoted (http://www.tcd.ie/Neuroscience/neil/interventions/hello-brain.php). There was a computer which displayed short ‘bite-size’ animated films about memory loss and brain health; these films can be viewed online at http://freedemliving.com.
The stand was manned by members of the NILVAD team, as well as research assistants from Trinity College Institute for Neuroscience.
During the Awareness Day, the staff spoke to members of the public about the various research projects underway within Trinity College and St James’s Hospital in the field of brain health, for example Destress, Relate, NEIL, Dempath, and NILVAD, thereby raising awareness of the study among a larger demographic of people within Dublin.
Below are two photos from the stand:
28 May 2014
Please find enclosed links to online advertisements for possible patients in the Netherlands
Flyer sent to former patients in the Netherlands
28 January 2013
New Scientific Advisor
Dr Sean Kennelly has agreed to join the TCD NILVAD team as the Scientific Medical Advisor. Sean has been providing advice informally to Coordinator Brian Lawlor regarding medical aspects for the trial during the submission and start up phases. He has agreed to come on board formally and provide his expertise and input during the clinical trial phase. Going forward we hope that Sean will also be able to contribute to the some of the scientific developments that will arise from our work.
09 January 2013
CBF substudies secures funding
Dr. Olga Meulenbroek, NILVAD partner from Stichting Katholieke Universiteit in Nijmegen, has recently received funding for the proposed substudies on cerebral blood flow. Here is what she has to say:
"With the idea for the CBF add-on study in mind, I embarked on writing a grant proposal. After a quarantine of days we were ready to submit to ADDF (Alzheimer’s Disease Drug Foundation) in April, which I had already contacted to inquire if they would even consider a proposal that would not fit their criteria in means of study-length. They would! And so the waiting started, until July when they told me: “Nice, but no…”. Upon reading the reviewers’ comments it became clear that all their issues could be solved, so I asked if we could go for a resubmission in October. We could!
Feeling doubtful about whether that would be a success, we also submitted the proposal to the Dutch Alzheimer Society in August. I felt the clock ticking. Another quarantine weekend arrived in the beginning of December, when ADDF asked me to clear some final issues for them, a.s.a.p., since they were rounding up their financial year. Hmmm is that a yes I’m reading between the lines there? Luckily Brian was able to send me some key documents that weekend, so I could submit my second rebuttal on Monday.
December progressed with still no word from the Dutch Alzheimer Society, but then as I was about to finish up for my Christmas holiday, the approval arrived by e-mail! What a huge relief to hear that the CBF add-on would be home free! This would require a small celebration with cake in January. And then there came this e-mail from ADDF on January 2nd…which encouraged me to buy not 1, but 2 cakes!"
23 July 2012
Meeting with European Commissioner
The coordinator Brian Lawlor had a chance to meet the European Commission for research, innovation and science at the official announcement of the FP7 HEALTH call for 2013.
26 June 2012
NILVAD project featured in "Dementia in Europe"
The NILVAD project is covered in the 11th Issue of "Dementia in Europe", a tri-annual magazine published by Alzheimer Europe dedicated to covering dementia policy at the European level. The magazine is distributed to all Members of the European Parliament, national Alzheimer associations as well as other interested parties.
21 May 2012
New Scientific Clinical Project Manager at Trinity College
The NILVAD project office welcomes Fiona Cregg to the NILVAD project team. Fiona started with the team on Tuesday May 15th as the Scientific Clinical Project Manager. She holds a BSc and Research Masters in Microbiology from National University of Ireland, Galway and a Diploma in Project Management from University of Limerick.
Prior to joining NILVAD, Fiona was involved in the project management of EU Framework 7 projects for an Irish SME called AquaTT, where she was project manager for the MarineTT project which AquaTT were coordinating. Fiona has over six years research management experience across the public and private sectors. Previous to AquaTT she was employed as Programme Management Co ordinator by the Research Office in University College Dublin and by the Irish Biotech company Biotrin where she lead Product Development projects for Biomarker products.
“The role of Scientific Clinical Project Manager with NILVAD is a perfect opportunity to merge my scientific and project management experience, to ensure the successful management of a challenging and highly complex project in a fascinating area.” Fiona Cregg
If you would like to get in touch with Fiona her email is creggf<at>tcd.ie or call +353 14162082